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    • The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC) 

      Sawada, Norie; Wark, Petra A.; Merritt, Melissa A.; Tsugane, Shoichiro; Ward, Heather A.; Rinaldi, Sabina; Weiderpass, Elisabete; Dartois, Laureen; His, Mathilde; Boutron-Ruault, Marie-Christine; Turzanski-Fortner, Renée; Kaaks, Rudolf; Overvad, Kim; Redondo, María-Luisa; Travier, Noemie; Molina-Portillo, Elena; Dorronsoro, Miren; Cirera, Lluis; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Lagiou, Pagona; Valanou, Elissavet; Masala, Giovanna; Pala, Valeria; Peeters, Petra H.M.; van der Schouw, Yvonne T.; Melander, Olle; Manjer, Jonas; da Silva, Marisa Eleonor; Skeie, Guri; Tjønneland, Anne; Olsen, Anja; Gunter, Mark J.; Riboli, Elio; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-03)
      Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly ...

    • Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study 

      Baumeister, Sebastian E.; Schlesinger, Sabrina; Aleksandrova, Krasimira; Jochem, Carmen; Jenab, Mazda; Gunter, Marc J.; Overvad, Kim; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Fournier, Agnès; Kühn, Tilman; Kaaks, Rudolf; Pischon, Tobias; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; La Vecchia, Carlo; Masala, Giovanna; Panico, Salvatore; Fasanelli, Francesca; Tumino, Rosario; Grioni, Sara; Bueno-de-Mesquita, Hendrik Bastiaan; Vermeulen, Roel; May, Anne M.; Borch, Kristin Benjaminsen; Oyeyemi, Sunday Oluwafemi; Ardanaz, Eva; Rodríguez-Barranco, Miguel; Chirlaque López, María Dolores; Felez-Nobrega, Mireia; Sonestedt, Emily; Ohlsson, Bodil; Hemmingsson, Oskar; Werner, Mårten; Perez-Cornago, Aurora; Ferrari, Pietro; Stepien, Magdalena; Freisling, Heinz; Tsilidis, Konstantinos K.; Ward, Heather; Riboli, Elio; Weiderpass, Elisabete; Leitzmann, Michael F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-22)
      <i>Background & Aims</i> - To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. We examined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC).<p><p> <i>Methods</i> - We identified 275 hepatocellular carcinoma (HCC) cases, 93 intrahepatic bile duct cancers (IHBCs), and 164 non-gallbladder ...

    • Association of circulating Vitamin D with colorectal cancer depends on Vitamin D-binding protein isoforms: A pooled, nested, case-control study 

      Gibbs, David Corley; Song, Mingyang; McCullough, Marjorie L.; Um, Caroline Y.; Bostick, Roberd M.; Wu, Kana; Flanders, W. Dana; Giovannucci, Edward; Jenab, Mazda; Brustad, Magritt; Tjønneland, Anne; Perez-Cornago, Aurora; Trichopoulou, Antonia; Tsilidis, Konstantinos K.; Hultdin, Johan; Gurrea, Aurelio Barricarte; Bueno-De-Mesquita, Bas; Mahamat-Saleh, Yahya; Kühn, Tilman; Gunter, Marc; Weiderpass, Elisabete; Fedirko, Veronika (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-15)
      <i>Background</i> - Higher circulating 25-hydroxyvitamin-D [25(OH)D] concentrations are consistently inversely associated with colorectal cancer (CRC) risk in observational studies. However, it is unknown whether this association depends on the functional GC-rs4588*A (Thr436Lys) variant encoding the vitamin D–binding protein-2 (DBP2) isoform, which may affect vitamin D status and bioavailability.< ...

    • Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study 

      Sedlmeier, Anja M.; Viallon, Vivian; Ferrari, Pietro; Peruchet-Noray, Laia; Fontvieille, Emma; Amadou, Amina; Seyed Khoei, Nazlisadat; Weber, Andrea; Baurecht, Hansjörg; Heath, Alicia K.; Tsilidis, Kostas; Kaaks, Rudolf; Katzke, Verena; Inan-Eroglu, Elif; Schulze, Matthias B.; Overvad, Kim; Bonet, Catalina; Ubago-Guisado, Esther; Chirlaque, María-Dolores; Ardanaz, Eva; Perez-Cornago, Aurora; Pala, Valeria; Tumino, Rosario; Sacerdote, Carlotta; Pasanisi, Fabrizio; Borch, Kristin Benjaminsen; Rylander, Charlotta; Weiderpass, Elisabete; Gunter, Marc J.; Fervers, Béatrice; Leitzmann, Michael F.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-02)
      Background - Classical anthropometric traits may fail to fully represent the relationship of weight, adiposity, and height with cancer risk. We investigated the associations of body shape phenotypes with the risk of overall and site-specific cancers.<p> <p>Methods - We derived four distinct body shape phenotypes from principal component (PC) analysis on height, weight, body mass index (BMI), waist ...

    • Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study 

      Mariosa, Daniela; Smith-Byrne, Karl; Richardson, Tom G.; Ferrari, Pietro; Gunter, Marc J.; Papadimitriou, Nikos; Murphy, Neil; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Riboli, Elio; Muller, David; Purdue, Mark P.; Chanock, Stephen J.; Hung, Rayjean J.; Amos, Christopher I.; O'Mara, Tracy A.; Amiano, Pilar; Pasanisi, Fabrizio; Rodriguez-Barranco, Miguel; Krogh, Vittorio; Tjønneland, Anne; Halkjær, Jytte; Perez-Cornago, Aurora; Chirlaque, María-Dolores; Skeie, Guri; Rylander, Charlotta; Borch, Kristin Benjaminsen; Aune, Dagfinn; Heath, Alicia K.; Ward, Heather A.; Schulze, Matthias; Bonet, Catalina; Weiderpass, Elisabete; Davey Smith, George; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-19)
      It is unclear if body weight in early life affects cancer risk independently of adult body weight. To investigate this question for 6 obesity-related cancers, we performed univariable and multivariable analyses using 1) Mendelian randomization (MR) analysis and 2) longitudinal analyses in prospective cohorts. Both the MR and longitudinal analyses indicated that larger early life body size was ...

    • Cigarette Smoking and Endometrial Cancer Risk: Observational and Mendelian Randomization Analyses 

      Dimou, Niki; Omiyale, Wemimo; Biessy, Carine; Viallon, Vivian; Kaaks, Rudolf; O'Mara, Tracy A.; Aglago, Elom K.; Ardanaz, Eva; Bergmann, Manuela M.; Bondonno, Nicola P.; Braaten, Tonje; Colorado-Yohar, Sandra M.; Crous-Bou, Marta; Dahm, Christina C.; Fortner, Renée T.; Gram, Inger Torhild; Harlid, Sophia; Heath, Alicia K.; Idahl, Annika; Kvaskoff, Marina; Nøst, Therese Haugdahl; Overvad, Kim; Palli, Domenico; Perez-Cornago, Aurora; Sacerdote, Carlotta; Sánchez, Maria-Jose; Schulze, Matthias B.; Severi, Gianluca; Simeon, Vittorio; Tagliabue, Giovanna; Tjønneland, Anne; Truong, Thérése; Tumino, Rosario; Johansson, Mattias; Weiderpass, Elisabete; Murphy, Neil; Gunter, Marc J.; Lacey, Ben; Allen, Naomi E.; Dossus, Laure (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-16)
      Background: Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of smoking in endometrial cancer risk, we conducted complementary observational and Mendelian randomization (MR) analyses.<p> <p>Methods: The observational analyses included 286,415 ...

    • Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia 

      Watts, Eleanor L.; Perez-Cornago, Aurora; Fensom, Georgina K.; Smith-Byrne, Karl; Noor, Urwah; Andrews, Colm D.; Gunter, Marc J.; Holmes, Michael V.; Martin, Richard M.; Tsilidis, Konstantinos K.; Albanes, Demetrius; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Chen, Chu; Cohn, Barbara A.; Dimou, Niki L.; Ferrucci, Luigi; Flicker, Leon; Freedman, Neal D.; Giles, Graham G.; Giovannucci, Edward L.; Goodman, Gary E.; Haiman, Christopher A.; Hankey, Graeme J.; Huang, Jiaqi; Huang, Wen-Yi; Hurwitz, Lauren M.; Kaaks, Rudolf; Knekt, Paul; Kubo, Tatsuhiko; Langseth, Hilde; Laughlin, Gail; Le Marchand, Loic; Luostarinen, Tapio; MacInnis, Robert J.; Mäenpää, Hanna O.; Männistö, Satu; Metter, E. Jeffrey; Mikami, Kazuya; Mucci, Lorelei A.; Olsen, Anja; Ozasa, Kotaro; Palli, Domenico; Penney, Kathryn L.; Platz, Elizabeth A.; Rissanen, Harri; Sawada, Norie; Schenk, Jeannette M.; Stattin, Pär; Tamakoshi, Akiko; Thysell, Elin; Tsai, Chiaojung Jillian; Tsugane, Shoichiro; Vatten, Lars Johan; Weiderpass, Elisabete; Weinstein, Stephanie J.; Wilkens, Lynne R.; Yeap, Bu B.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-17)
      Previous studies had limited power to assess the associations of testosterone with aggressive disease as a primary endpoint. Further, the association of genetically predicted testosterone with aggressive disease is not known. We investigated the associations of calculated free and measured total testosterone and sex hormone-binding globulin (SHBG) with aggressive, overall and early-onset prostate ...

    • Citrus intake and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Cervenka, Iris; Al-Rahmoun, Marie; Mancini, Francesca R.; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Trichopoulou, Antonia; Peppa, Eleni; La Vecchia, Carlo; Overvad, Kim; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Perez-Cornago, Aurora; Jakszyn, Paula; Grioni, Sara; Schulze, Matthias B.; Skeie, Guri; Lasheras, Christina; Colorado-Yohar, Sandra; RodrÍguez-Barranco, Miguel; Kühn, Tilman; Katzke, Verena A.; Amiano, Pilar; Tumino, Rosario; Panico, Salvatore; Ezponda, Ana; Sonestedt, Emily; Scalbert, Augustin; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-24)
      Citrus intake has been suggested to increase the risk of skin cancer. Although this relation is highly plausible biologically, epidemiologic evidence is lacking. We aimed to examine the potential association between citrus intake and skin cancer risk. EPIC is an ongoing multi-center prospective cohort initiated in 1992 and involving ~ 520,000 participants who have been followed-up in 23 centers from ...

    • Comparing Calculated Nutrient Intakes Using Different Food Composition Databases: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort 

      Van Puyvelde, Heleen; Perez-Cornago, Aurora; Casagrande, Corinne; Nicolas, Geneviève; Versele, Vickà; Skeie, Guri; Schulze, Matthias B.; Johansson, Ingegerd; Huerta, José María; Oliverio, Andreina; Ricceri, Fulvio; Halkjær, Jytte; Etxezarreta, Pilar Amiano; Van Herck, Koen; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
      This study aimed to compare calculated nutrient intakes from two different food composition databases using data from the European prospective investigation into cancer and nutrition (EPIC) cohort. Dietary intake data of the EPIC cohort was recently matched to 150 food components from the U.S. nutrient database (USNDB). Twenty-eight of these nutrients were already included in the EPIC nutrient ...

    • Consumption of Fish and Long-chain n-3 Polyunsaturated Fatty Acids Is Associated With Reduced Risk of Colorectal Cancer in a Large European Cohort 

      Aglago, Elom Kouassivi; Huybrechts, Inge; Murphy, Neil; Casagrande, Corinne; Nicolas, Geneviève; Pischon, Tobias; Fedirko, Veronika; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Fournier, Agnès; Katzke, Verena Andrea; Kühn, Tilman; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Lasheras, Cristina; Agudo, Antonio; Sanchez, Maria-Jose; Amiano, Pilar; Huerta, Jose Maria; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Bueno-De-Mesquita, Bas; May, Anne; Derksen, Jeroen W.G.; Hellstrand, Sophie; Ohlsson, Bodil; Wennberg, Maria; Van Guelpen, Bethany; Skeie, Guri; Brustad, Magritt; Weiderpass, Elisabete; Cross, Amanda J.; Ward, Heather; Riboli, Elio; Norat, Teresa; Chajes, Veronique; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
      Background & Aims - There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. ...

    • Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study 

      Cordova, Reynalda; Kliemann, Nathalie; Huybrechts, Inge; Rauber, Fernanda; Vamos, Eszter P.; Levy, Renata Bertazzi; Wagner, Karl-Heinz; Viallon, Vivian; Casagrande, Corinne; Nicolas, Geneviève; Dahm, Christina Catherine; Zhang, Jie; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Chiristine; Mancini, Francesca Romana; Laouali, Nasser; Katzke, Verena; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; van der Schouw, Yvonne T; Derksen, Jeroen W.G.; Rylander, Charlotta; Skeie, Guri; Jakszyn, Paula; Rodríguez-Barranco, Miguel; Huerta, José María; Barricarte, Aurelio; Brunkwall, Louise; Ramne, Stina; Bodén, Stina; Perez-Cornago, Aurora; Heath, Alicia K; Vineis, Paolo; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher J.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Background - There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity.<p> <p>Methods - This prospective cohort included 348 748 men and women aged 25–70 years. Participants were recruited between 1992 and 2000 from 9 European ...

    • Dietary advanced glycation end-products and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study 

      Aglago, Elom K.; Mayén, Ana-Lucia; Knaze, Viktoria; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Eriksen, Anne Kirstine; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B.; Birukov, Anna; Palli, Domenico; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Bas; Derksen, Jeroen W.G.; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Quirós, J. Ramón; Lujan-Barroso, Leila; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Johansson, Ingegerd; Manjer, Jonas; Perez-Cornago, Aurora; Weiderpass, Elisabete; Gunter, Marc; Heath, Alicia K.; Schalkwijk, Casper G.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
      Dietary advanced glycation end-products (dAGEs) have been hypothesized to be associated with a higher risk of colorectal cancer (CRC) by promoting inflammation, metabolic dysfunction, and oxidative stress in the colonic epithelium. However, evidence from prospective cohort studies is scarce and inconclusive. We evaluated CRC risk associated with the intake of dAGEs in the European Prospective ...

    • Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries 

      Steur, Marinka; Johnson, Laura; Sharp, Stephen J.; Imamura, Fumiaki; Sluijs, Ivonne; Key, Timothy J.; Wood, Angela M.; Chowdhury, Rajiv; Guevara, Marcela; Jakobsen, Marianne Uhre; Johansson, Ingegerd; Koulman, Albert; Overvad, Kim; Sánchez, Maria-José; van der Schouw, Yvonne T.; Trichopoulou, Antonia; Weiderpass, Elisabete; Wennberg, Maria; Zheng, Ju-Sheng; Boeing, Heiner; Boer, Jolanda M. A.; Boutron-Ruault, Marie-Christine; Ericson, Ulrika; Heath, Alicia K.; Huybrechts, Inge; Imaz, Liher; Kaaks, Rudolf; Krogh, Vittorio; Kühn, Tilman; Kyrø, Cecilie; Masala, Giovanna; Melander, Olle; Moreno-Iribas, Conchi; Panico, Salvatore; Quirós, José R.; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Santiuste, Carmen; Skeie, Guri; Tjønneland, Anne; Tumino, Rosario; Monique Verschuren, Verschuren; Zamora-Ros, Raúl; Dahm, Christina C.; Perez-Cornago, Aurora; Schulze, Matthias B.; Tong, Tammy Y.N.; Riboli, Elio; Wareham, Nick; Danesh, John; Butterworth, Adam S.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain.<p> METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...

    • Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort 

      Zamora-Ros, Raul; Barupal, Dinesh Kumar; Rothwell, Joseph A.; Jenab, Mazda; Fedirko, Veronika; Romieu, Isabelle; Aleksandrova, Krasimira; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Affret, Aurélie; His, Mathilde; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; Naska, Androniki; Kritikou, Maria; Saieva, Calogero; Agnoli, Claudia; Santucci de Magistris, Maria; Tumino, Rosario; Fasanelli, Francesca; Weiderpass, Elisabete; Skeie, Guri; Merino, Susana; Jakszyn, Paula; Sánchez, María-José; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Sonestedt, Emily; Ericson, Ulrika; Maria Nilsson, Lena; Bodén, Stina; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Perez-Cornago, Aurora; Wareham, Nicholas J.; Khaw, Kay-Thee; Freisling, Heinz; Cross, Amanda J.; Riboli, Elio; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-22)
      Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in colorectal cancer (CRC) development remains sparse and inconsistent. We evaluated the association between dietary intakes of total flavonoids and their subclasses and risk of ...

    • Dietary Intake of Advanced Glycation End Products (AGEs) and Mortality among Individuals with Colorectal Cancer 

      Mao, Ziling; Aglago, Elom K.; Zhao, Zhiwei; Schalkwijk, Casper C; Jiao, Li; Freisling, Heinz; Weiderpass, Elisabete; Hughes, David J.; Eriksen, Anne Kirstine; Tjønneland, Anne; Gianluca, Severi; Rothwell, Joseph A; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kaaks, Rudolf; Birukov, Anna; Schulze, Matthias B; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Gram, Inger Torhild; Skeie, Guri; Sandanger, Torkjel M; Quiros, J Ramon; Crous-Bou, Marta; Sanchez, Maria-Jose; Amiano, Pilar; Chirlaque, Maria-Dolores; Barricarte Gurrea, Aurelio; Manjer, Jonas; Johansson, Ingegerd; Perez-Cornago, Aurora; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Advanced glycation end-products (AGEs) may promote oxidative stress and inflammation and have been linked to multiple chronic diseases, including cancer. However, the association of AGEs with mortality after colorectal cancer (CRC) diagnosis has not been previously investigated. Multivariable Cox proportional hazards models were used to calculate hazard ratios and corresponding 95% confidence ...

    • Dietary intake of advanced glycation endproducts (AGEs) and cancer risk across more than 20 anatomical sites: A multinational cohort study 

      Córdova, Reynalda; Mayén, Ana-Lucia; Knaze, Viktoria; Aglago, Elom Kouassivi; Schalkwijk, Casper; Wagner, Karl-Heinz; Overvad, Kim; Tjønneland, Anne; Kyrø, Cecilie; Katzke, Verena Andrea; Cornet, Charlotte Le; Schulze, Matthias Bernd; Birukov, Anna; Palli, Domenico; Grioni, Sara; Pasanisi, Fabrizio; Catalano, Alberto; Sandanger, Torkjel M; Gram, Inger Torhild; Skeie, Guri; Crous-Bou, Marta; Molina-Montes, Esther; Amiano, Pilar; Colorado-Yohar, Sandra Milena; Ardanaz, Eva; Drake, Isabel; Manjer, Jonas; Johansson, Ingegerd; Esberg, Anders; Perez-Cornago, Aurora; Weiderpass, Elisabete; Jenab, Mazda; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-04)

    • Evaluation of protein and amino acid intake estimates from the EPIC dietary questionnaires and 24-h dietary recalls using different food composition databases 

      Iguacel, Isabel; Perez-Cornago, Aurora; Schmidt, Julie A.; Van Puyvelde, Heleen; Travis, Ruth; Casagrande, Corinne; Nicolas, Genevieve; Riboli, Elio; Weiderpass, Elisabete; Ardanaz, Eva; Barricarte, Aurelio; Bodén, Stina; Bruno, Eleonora; Ching-López, Ana; Aune, Dagfinn; Jensen, Torill; Ericson, Ulrika; Johansson, Ingergerd; Ma Huerta, José; Katzke, Verena; Kühn, Tilman; Sacerdote, Carlotta; Schulze, Matthias B.; Skeie, Guri; Ramne, Stina; Ward, Heather; Gunter, Marc J.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)
      Background and aims: This study aimed to expand the European Prospective Investigation into Cancer and Nutrition (EPIC) nutrient database (ENDB) by adding amino acid (AA) values, using the U.S. nutrient database (USNDB). Additionally, we aimed to evaluate these new protein and AA intake estimates from the EPIC dietary questionnaires (DQ) and 24- h dietary recalls (24-HDR) using different matching ...

    • Food processing and cancer risk in Europe: results from the prospective EPIC cohort study 

      Kliemann, Nathalie; Rauber, Fernanda; Bertazzi Levy, Renata; Viallon, Vivian; Vamos, Eszter P; Cordova, Reynalda; Freisling, Heinz; Casagrande, Corinne; Nicolas, Genevieve; Aune, Dagfinn; Tsilidis, Konstantinos K; Heath, Alicia; Schulze, Matthias B; Jannasch, Franziska; Srour, Bernard; Kaaks, Rudolf; Rodriguez-Barranco, Miguel; Tagliabue, Giovanna; Agudo, Antonio; Panico, Salvatore; Ardanaz, Eva; Chirlaque, María-Dolores; Vineis, Paolo; Tumino, Rosario; Perez-Cornago, Aurora; Andersen, Julie Louise Munk; Tjønneland, Anne; Skeie, Guri; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-06)
      Background - Food processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according to amount of food processing and risk of cancer at 25 anatomical sites using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.<p> ...

    • Hepcidin levels and gastric cancer risk in the EPIC-EurGast study 

      Jakszyn, Paula; Fonseca-Nunes, Ana; Lujan-Barroso, Leila; Aranda, Núria; Tous, Monica; Arija, Victoria; Cross, Amanda; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Kühn, Tilman; Kaaks, Rudolf; Sjöberg, Klas; Tumino, Rosario; Palli, Domenico; Ricceri, Fulvio; Fasanelli, Francesca; Krogh, Vittorio; Mattiello, Amalia; Jenab, Mazda; Gunter, Marc; Perez-Cornago, Aurora; Khaw, Kay-Tee; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Trichopoulou, Antonia; Peppa, Eleni; Vasilopoulou, Effie; Boeing, Heiner; Sánchez-Cantalejo, Emilio; Dorronsoro, Miren; Barricarte, Aurelio; Quiros, Jose Maria; Peeters, Petra H; Agudo, Antonio (Journal article; Tidsskriftartikkel, 2017-06-21)
      Hepcidin is the main regulator of iron homeostasis and dysregulation of proteins involved in iron metabolism has been associated with tumorogenesis. However, to date, no epidemiological study has researched the association between hepcidin levels and gastric cancer risk. To further investigate the relationship between hepcidin levels and gastric cancer risk, we conducted a nested case-control study ...

    • Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study 

      Moskal, Aurelie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T.; Jenab, Mazda; Ferrari, Pietro; Tjønneland, Anne; Petersen, Kristina E N; Dahm, Christina C; Hansen, Camilla Plambeck; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Cadeau, Claire; Kuhn, Tilman; Katzke, Verena; Iqbal, Khalid; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Masala, Giovanna; de Magistris, Maria Santucci; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Peeters, Petra H; Bueno-de-Mesquita, Bas H; Engeset, Dagrun; Licaj, Idlir; Skeie, Guri; Ardanaz, Eva; Buckland, Genevieve; Castaño, José María Huerta; Quirós, José R.; Amiano, Pilar; Molina-Portillo, Elena; Winkvist, Anna; Myte, Robin; Ericson, Ulrika; Sonestedt, Emily; Perez-Cornago, Aurora; Wareham, Nick; Khaw, Kay-Tee; Huybrechts, Inge; Tsilidis, Konstantinos K; Ward, Heather; Gunter, Marc J; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-20)
      Background: Much of the current literature on diet–colorectal cancer (CRC) associations focused on studies of single foods/ nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. <p>Methods: Among 477 312 participants, ...